| # | Fact |
|---|
| 1 | Former stepson of Darlene Sammons. |
| 2 | Father-in-law of Todd Morgan (Rosanna's fourth husband) and Christina McLarty (David's second wife). |
| 3 | Studied at Lee Strasberg's Actors Studio in New York. Worked at various times as comic, musician and puppeteer. |
| 4 | Grandfather of Coco Arquette and Charlie West Arquette (David's children), Zoe Sidel (Rosanna's daughter), Enzo Rossi and Harlow Olivia Calliope Elliott (Jane) (Patricia's children). |
| 5 | Frequently appeared in movies with his sons. |
| 6 | Former father-in-law of actors Nicolas Cage, Thomas Jane (Patricia's former husbands), Courteney Cox (David's first wife) Tony Greco, James Newton Howard, John Sidel (Rosanna's former husbands). |
| 7 | Son of Cliff Arquette and Julie Harrison. Son-in-law of Joseph Nowak and Claire Hibel. |
| 8 | Father of Rosanna Arquette, Patricia Arquette, Alexis Arquette, Richmond Arquette, and David Arquette. |
| Title | Year | Status | Character |
|---|
| Murder One | 1997 | TV Series | Judge Robert Beame |
| Adventures from the Book of Virtues | 1997 | TV Series | Old Man Rabbit / The Salesman |
| Meet Wally Sparks | 1997 | | Cardinal |
| Murder One: Diary of a Serial Killer | 1997 | TV Mini-Series | |
| Kid Cop | 1996 | Video | Mayor Cosgrove |
| Mojave Moon | 1996 | | Charlie |
| The Real Adventures of Jonny Quest | 1996 | TV Series | Civilian / Driver |
| Waiting for Guffman | 1996 | | Clifford Wooley |
| Hypernauts | 1996 | TV Series | Horten |
| Babylon 5 | 1996 | TV Series | General Smits |
| Fox Hunt | 1996 | | The Wolf |
| Seinfeld | 1995 | TV Series | Leapin' Larry |
| Wild Side | 1995 | | The Chief |
| Stuart Saves His Family | 1995 | | Cemetery Official |
| SeaQuest 2032 | 1995 | TV Series | Kearny |
| Daisy-Head Mayzie | 1995 | TV Short | Principal (voice) |
| Capitol Critters | 1995 | TV Series | |
| The Flintstones: Wacky Inventions | 1994 | Video short | Prof, Einstone (voice) |
| Saved by the Bell: The New Class | 1994 | TV Series | Uncle Lester |
| Freddy Pharkas, Frontier Pharmacist | 1994 | Video Game | Whittlin' Willie / P. H. Balance (voice) |
| Sleep with Me | 1994 | | Minister |
| Menendez: A Killing in Beverly Hills | 1994 | TV Movie | Lyle's Jury: Juror #3 |
| Fox Hunt | 1993 | Video Game | The Wolf |
| Attack of the 50 Ft. Woman | 1993 | TV Movie | Mr. Ingersol |
| Swat Kats: The Radical Squadron | 1993 | TV Series | Abner Dolittle |
| Tainted Blood | 1993 | TV Movie | Artie |
| Tom & Jerry Kids Show | 1993 | TV Series | |
| Let's Kill All the Lawyers | 1992 | | Antinus |
| A Child Lost Forever: The Jerry Sherwood Story | 1992 | TV Movie | Walter Vinton |
| Beverly Hills, 90210 | 1992 | TV Series | Priest |
| L.A. Law | 1992 | TV Series | Inspector Dodek |
| Double Trouble | 1992/I | | Tarlow |
| Camp Candy | 1989-1992 | TV Series | Rex DeForest III |
| Candid Camera | 1991 | TV Series | Lawyer |
| Yo Yogi! | 1991 | TV Series | Bombastic Bobby |
| The Linguini Incident | 1991 | | Texas Joe |
| Morton & Hayes | 1991 | TV Series | Mr. Caldicott |
| Rock 'n' Roll High School Forever | 1991 | | Mr. Cheese |
| Get a Life | 1991 | TV Series | Justice of the Peace |
| Dragnet | 1990 | TV Series | Mr. Wolfe |
| Matlock | 1990 | TV Series | 2nd Commissioner |
| Syngenor | 1990 | | Ethan Valentine |
| Book of Love | 1990 | | Mr. Malloy |
| Captain Planet and the Planeteers | 1990 | TV Series | Additional Voices (voice) |
| Gravedale High | 1990 | TV Series voice | |
| Tales from the Crypt | 1990 | TV Series | Ernest Feeley |
| Walt Disney's Wonderful World of Color | 1990 | TV Series | Screenwriter |
| Tango & Cash | 1989 | | Wyler |
| Dad | 1989 | voice | |
| Astérix et le coup du menhir | 1989 | | Additional voices (American dub) (English version, voice) |
| Chopper Chicks in Zombietown | 1989 | | Sheriff Bugiere |
| Charles in Charge | 1989 | TV Series | Clarence Lembeck |
| Kiki's Delivery Service | 1989 | | Additional Voices (English version, voice) |
| The Horror Show | 1989 | | Lt. Miller |
| Quantum Leap | 1989 | TV Series | Father Muldooney |
| Studio 5-B | 1989 | TV Series | Shelly |
| Guns of Paradise | 1988-1989 | TV Series | Mr. Sinclair |
| A Very Brady Christmas | 1988 | TV Movie | Sam / Santa |
| My First Love | 1988 | TV Movie | Mark Grossman |
| Brothers | 1988 | TV Series | Mr. Stoner |
| Dance 'Til Dawn | 1988 | TV Movie | Pawnbroker |
| The Canterville Ghost | 1988 | TV Movie | Hiram B. Otis (voice, as Louis Arquette) |
| A Pup Named Scooby-Doo | 1988 | TV Series | Additional Voices (voice) |
| Akira | 1988 | | Doctor (1989 Streamline Pictures dub) / Council 2 (1989 Streamline Pictures dub) / Senator (1989 Streamline Pictures dub) / ... (English version, voice, as Lewis Lemay) |
| The Great Outdoors | 1988 | | Herm |
| Big Business | 1988 | | Mr. Stokes |
| The Real Ghostbusters | 1987 | TV Series | Head Demon / Micawb |
| ALF | 1987 | TV Series | Ed Billings |
| The Smurfs | 1987 | TV Series | Additional Voices |
| CBS Summer Playhouse | 1987 | TV Series | Mr. Schluter |
| ABC Afterschool Specials | 1987 | TV Series | Dr. Kolovson |
| Married with Children | 1987 | TV Series | Ed |
| Gimme a Break! | 1982-1987 | TV Series | Coach Henderson / Kramer |
| Mama's Family | 1987 | TV Series | Grand Viper |
| Perfect Strangers | 1987 | TV Series | Rowdy Hockey Fan #1 |
| Rocky Road | 1985-1986 | TV Series | Lucas Buchanan |
| Tall Tales & Legends | 1986 | TV Series | George / Jimbo Smith / Narrator |
| Nobody's Fool | 1986 | | Mr. Fry |
| Sledge Hammer! | 1986 | TV Series | Jacob |
| The Check Is in the Mail... | 1986 | | Man at pool |
| Just Between Friends | 1986 | | TV Station Guard |
| Rock 'n' Wrestling | 1985-1986 | TV Series | Superfly Jimmy Snuka |
| The Fall Guy | 1985 | TV Series | Ghost |
| Badge of the Assassin | 1985 | TV Movie | Foreman #1 |
| Sherlock Hound | 1984-1985 | TV Series | Dr. Watson |
| Down to Earth | 1985 | TV Series | Chester Chomski |
| E/R | 1984 | TV Series | Arnie Popkin |
| Challenge of the GoBots | 1984 | TV Series | Additional Voices (voice) |
| St. Elsewhere | 1984 | TV Series | Judge Ellsworth |
| Matt Houston | 1984 | TV Series | City Councilman Roberts |
| Riptide | 1984 | TV Series | Sidney Gorman |
| Remington Steele | 1983 | TV Series | Stuart Thorpe |
| Off the Wall | 1983 | | Prison Chaplain |
| Prime Times | 1983 | TV Movie | Various |
| Strike Force | 1982 | TV Series | Zack / Hopkins |
| Dallas | 1982 | TV Series | |
| Private Benjamin | 1982 | TV Series | Salesman |
| Harper Valley P.T.A. | 1981-1982 | TV Series | Lyle Oliver / Officer |
| Simon & Simon | 1982 | TV Series | Matt |
| The Incredible Hulk | 1981 | TV Series | Les Creaseman |
| The Waltons | 1978-1981 | TV Series | Jefferson Davis 'J.D.' Pickett |
| Fantasy Island | 1978-1981 | TV Series | Slocumb / Fred Waters / Jeff Logan |
| Pray TV | 1980 | | Fred Wilson |
| The Jayne Mansfield Story | 1980 | TV Movie | Publicity Man |
| Tenspeed and Brown Shoe | 1980 | TV Series | Lieber |
| Mrs. Columbo | 1979 | TV Series | Howard |
| The China Syndrome | 1979 | | Hatcher |
| Delta House | 1979 | TV Series | Mr. Kroger |
| Barney Miller | 1979 | TV Series | Nells Finney |
| Rescue from Gilligan's Island | 1978 | TV Movie | Judge |
| Coming Attractions | 1978 | | Warden |
| Ruby and Oswald | 1978 | TV Movie | |
| Lou Grant | 1978 | TV Series | National Editor / Airline Official |
| Man from Atlantis | 1977 | TV Series | Friar Laurence |
| Alice | 1977 | TV Series | Officer Hertzig |
| The Very Naked Canvas | 1965 | as Mike Arquette | |
| As Told by Ginger | 2000-2001 | TV Series | Mr. Cilia |
| Out Cold | 2001 | | Papa Muntz |
| FreakyLinks | 2001 | TV Series | Bob Frewer |
| Escape from Monkey Island | 2000 | Video Game | Freddie (voice) |
| Little Nicky | 2000 | | Cardinal |
| Best in Show | 2000 | | Fern City Show Spectator |
| Ready to Rumble | 2000 | | Fred King |
| Spawn | 1997-1999 | TV Series | Additional Voices |
| Almost Heroes | 1998 | | Merchant |
| Twilight | 1998 | | Water Pistol Man |
| Adventures with Barbie: Ocean Discovery | 1997 | Video Game voice | |
| River Made to Drown In | 1997 | | Vagabond |
| Scream 2 | 1997 | | Chief Hartley |
| Born Bad | 1997 | | Bank Manager |
| Sleepwalkers | 1997 | TV Series | |
| Kiss & Tell | 1997 | | Inspector Dan Furbal |
| The Westing Game | 1997 | TV Movie | Otis Amber |
| The Alarmist | 1997 | | Bruce Hudler |
| Spicy City | 1997 | TV Series | Corbin / Farfelson |
| Princess Mononoke | 1997 | | Additional Voices (English version, voice) |
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